Researchers use epigenetic clock, DNA methylation and mouse model to demonstrate that T cell proliferation can stretch past organism lifespan and acuta lymphoblastic leukemia T cells appear hundreds ...

A series of preclinical studies show that a new compound, SHP1705, targets circadian clock proteins hijacked by glioblastoma stem cells, impairing the cancer cells’ ability to survive and grow.

Most biochemical reactions accelerate as temperature increases, but our daily circadian rhythms, which are underlain by gene regulatory and biochemical networks, remain constant, even as temperatures ...

St. Jude co-corresponding authors Caitlin Zebley, MD, PhD, Department of Bone Marrow Transplantation & Cellular Therapy and Ben Youngblood, PhD, Department of Immunology, used an epigenetic clock to ...