Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is ...

Breast cancer is one the leading causes of cancer death among women globally. Upon breast cancer diagnosis, the testing of HER2—a protein that promotes cancer cell growth, is routinely carried out to ...

Leveraging trusted automation from Leica Biosystems, HCR™ Gold IF helps researchers move from tissue to insight faster with ...

Researchers at the Paul Scherrer Institute PSI have developed an AI platform that stains tissue images from computed ...

Traditional histopathology, crucial for disease diagnosis, relies on chemically staining tissue samples to highlight cellular structures for microscopic examination by pathologists. This ...

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do ...

Staining is a crucial step in histopathology that prepares tissue sections for microscopic examination. Hematoxylin and eosin (H&E) staining, also known as basic or routine staining, is used in 80% of ...

Understanding cellular function within a given microenvironment is currently an expectation rather than the exception in life sciences research. Cell- and tissue-specific relationships determine ...

Tumor microenvironment is a complex assembly of cancer cells, immune cells, stromal cells, and extracellular matrix components. Interactions between these components can significantly impact tumor ...

High-resolution mapping of three-dimensional structures in biological tissues is essential for understanding various biological processes. However, the optical heterogeneity of these tissues, marked ...

Researchers from the University of Eastern Finland, the University of Turku, and Tampere University have developed an artificial intelligence-based method for virtual staining of histopathological ...

Deep neural networks have already been applied to stain unlabeled tissue section images, avoiding different laborious and time-consuming histochemical staining processes. There are, however, some ...