New understanding about the pathophysiology of the condition, along with new clinical trial endpoints for approval, have ...

In January 2025, PowerSchool’s student information system was hacked, exposing the names, addresses and other information of more than tens of millions of schoolchildren and their parents. “Private ...

Secretory IgA (SIgA) serves as the first line of defense in protecting the intestinal epithelium from enteric toxins and pathogenic microorganisms. Through a process known as immune exclusion, SIgA ...

IgA nephropathy, or Berger’s disease, is a chronic kidney condition with varying symptoms and progression rates. Some may experience no symptoms for years. There is no cure for IgA nephropathy, but ...

IgA nephropathy (IgAN) is a kidney disorder caused by a buildup of immune complexes and the antibody called immunoglobulin A (IgA) inside the kidneys. This buildup causes inflammation in the kidneys.

IgA nephropathy is a relatively newly recognized disease, first described by Berger and Hinglais in 1968. 1 It is now generally known to be the most common form of primary glomerulonephritis ...

Panel A (periodic acid–Schiff stain) shows mesangial hypercellularity, with four or more cells per mesangial area (arrow). Panel B (periodic acid–Schiff stain) shows segmental endocapillary ...