Dendritic cells (DCs) have emerged in the field of cancer immunotherapy as the most potent professional antigen-presenting ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

A study shows mitochondrial electron flow keeps dendritic cells primed, regulating gene activity and T-cell activation. The ...

NUFIP1 in Sepsis: Regulating Immune Function and Organ Dysfunction. This illustration demonstrates the pivotal role of NUFIP1-mediated ribophagy in dendritic cell activation and sepsis-induced immune ...

The immune system has evolved to mount immune responses against foreign pathogens and to remain silent against self-antigens. A balance between immunity and tolerance is required as any disturbance ...

The immune system is a complex response of various cells that detect and elicit mechanisms to eliminate disease. This ...

Hypoxia, or local lack of oxygen, which develops in aggressive cancer tumors is one of the main obstacles to the ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

Findings identify strategy for boosting anticancer immunity and potentially a new tool for delivering genetic payloads to ...

A type of rare T cell triggers a cascade of signals amplifying inflammation and ultimately leading to liver fibrosis, ...