Path analysis requires that exogenous and residual variables not be correlated. An alterna- tive to assuming the two to be independent is to treat the exogenous variables as fixed or non-random.

Endogenous insulin secretion is sustained by pancreatic β cells to maintain blood glucose levels within a narrow range and its impairment is a prerequisite for the development of hyperglycemia ...

The application of polygenic scores has transformed our ability to investigate whether and how genetic and environmental factors jointly contribute to the variation of complex traits. Modelling the ...