Serially cloned mice hit a genetic “dead end” by generation 58, underscoring that sex evolved for variation, purging harmful ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

Learn more about new research that analyzed 16,000 ancient genomes and discovered that natural selection hasn’t slowed down.

Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at replication origins, ensuring proper replication timing, and improving ...

It did not take long after the discovery of X-rays in the 1890s for scientists to begin exploring the harmful effects of ...

Hidden within fish DNA are powerful genetic twists that may explain one of nature’s biggest mysteries: how new species form so quickly. In Lake Malawi, hundreds of cichlid fish species evolved at ...

Scientists used a bacterial system called retron to turn DNA into a programmable tool inside living cells, enabling gene ...

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer. Drs Ursula A. Matulonis and Panagiotis A. Konstantinopoulos discuss ...