We conducted a phase 2–3 double-blind trial to assess the efficacy and safety of nirmatrelvir–ritonavir in asymptomatic, rapid antigen test–negative adults who had been exposed to a household contact ...
Simnotrelvir is an oral 3-chymotrypsin–like protease inhibitor that has been found to have in vitro activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and potential efficacy ...
Severe COVID-19 is defined as SARS-CoV-2 infection with hypoxemia, respiratory distress (respiratory rate >30), and/or severe pneumonia on imaging (>50% infiltrates). 46, 47 Patients with ...
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